Alcohols and polyols
- (1)
- (55)
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- (39)
- (4)
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- (1)
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- (153)
- (1)
- (65)
- (27)
- (14)
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- (1)
- (1)
- (10)
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- (2)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (6)
- (2)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (61)
- (13)
- (14)
- (1)
- (2)
- (1)
- (26)
- (6)
- (4)
- (1)
- (6)
- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
- (7)
- (10)
- (145)
- (114)
- (6)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (2)
- (4)
- (1)
- (2)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (2)
- (5)
- (4)
- (33)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (17)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (2)
- (10)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (1)
- (5)
- (3)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (1)
- (2)
- (8)
- (2)
- (3)
- (3)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (1)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
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- (4)
- (1)
- (1)
- (3)
- (2)
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- (1)
- (1)
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- (7)
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- (2)
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- (7)
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- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
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- (1)
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- (1)
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- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
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- (3)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
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- (1)
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- (5)
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- (2)
- (1)
- (1)
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- (9)
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- (1)
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- (9)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (27)
- (2)
- (1)
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- (1)
- (4)
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- (4)
- (3)
- (2)
- (7)
- (2)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (21)
- (16)
- (1)
- (2)
- (20)
- (2)
- (2)
- (3)
- (67)
- (1)
- (1)
- (1)
- (4)
- (8)
- (1)
- (2)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (2)
- (2)
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- (9)
- (6)
- (8)
- (4)
- (1)
- (1)
- (1)
- (1)
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- (3)
- (6)
- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (85)
- (1)
- (5)
- (72)
- (3)
- (5)
- (237)
- (4)
- (2)
- (2)
- (21)
- (279)
- (17)
- (1)
- (6)
- (273)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (6)
- (3)
- (1)
- (4)
- (21)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (704)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
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- (66)
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- (33)
- (2)
- (31)
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- (11)
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Filtered Search Results
Medchemexpress LLC GYKI 53655 hydrochloride | 143692-48-2 | MFCD01941362 | 98.4% | 388.85 g/mol | C19H21ClN4O3 | 50 MG
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GYKI 53655 hydrochloride is the hydrochloride salt of GYKI 53655, a selective antagonist of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors used as a research tool in neuropharmacology. The compound is supplied as a light yellow solid with high purity and documented solubility properties.
- Selective antagonist of AMPA receptors for neuropharmacology research.
- High purity suitable for in vitro pharmacology.
- Soluble in DMSO and partially soluble in water with warming or sonication.
- Supplied as a solid with recommended storage at 4°C, protected from moisture.
- Molecular weight 388.85 g/mol and formula C19H21ClN4O3.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 25 MG
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Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. It inhibits estrogen production in hamster ovarian slices and has various in vivo effects, including the prevention of certain tumors and reduction of parasite burden.
- Potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
- Inhibits estrogen production with an IC50 of 0.03 μM.
- Inhibits progesterone production with an IC50 of 120 μM.
- Inhibits aromatase-mediated uterine hypertrophy in immature female rats with an oral ED50 of 0.03 mg/kg.
- Prevents development of benign and malignant spontaneous mammary neoplasms.
- Slows spontaneous development of pituitary pars distalis adenomas.
- Reduces incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Vu6036720 hydrochloride | 3026597-12-3 | 99.7% | 473.39 | C20H23Cl2FN4O2S | 10 MG
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VU6036720 hydrochloride is the hydrochloride salt of a potent, selective in vitro inhibitor of heteromeric Kir4.1/5.1 inward-rectifier potassium channels, used for research into neural and renal channel function. The compound is supplied as a high-purity solid suitable for biochemical and electrophysiological assays.
- Potent Kir4.1/5.1 inhibition with IC50 0.24 μM.
- High purity suitable for research applications.
- Available in small solid quantities for assay workflows.
- Stable solid with recommended sealed storage at 4°C.
- Compatible with DMSO stock preparations for in vitro testing.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC ARG1-IN-1 hydrochloride | 00-00-0 | 90.0% | C11H22BClN2O4 | 10MG
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ARG1-IN-1 hydrochloride is a research compound that selectively inhibits human arginase 1, with a reported IC50 of 29 nM. Supplied as the hydrochloride salt, the material is typically offered at 90.0% purity and is intended for biochemical and pharmacological research applications only.
- Potent arginase 1 inhibition (IC50 = 29 nM).
- Supplied as a hydrochloride salt for chemical stability.
- Typical purity 90.0% suitable for research use.
- Appropriate for in vitro biochemical and cell-based assays.
- Provided in milligram-scale quantities for laboratory studies.
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Medchemexpress LLC Pitolisant hydrochloride | 903576-44-3 | ≥98.0% | 10 MG
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Pitolisant hydrochloride is a potent, selective nonimidazole inverse agonist of the human histamine H3 receptor supplied as a research-grade hydrochloride salt for laboratory use.
- High potency (Ki = 0.16 nM).
- Research reagent for in vitro pharmacology and receptor studies.
- White to beige powder, supplied in small quantities for laboratory use (e.g., 10 MG).
- Purity ≥98.0% (HPLC) as commonly reported for research-grade material.
- Stable when stored sealed and away from moisture; in solvent store at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Guanabenz hydrochloride | 23113-43-1 | 99.9% | 25 MG
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Guanabenz hydrochloride is an orally active α-2-adrenoceptor agonist with antihypertensive and antiparasitic activity. It interferes with ER stress-signalling and has protective effects in cardiac myocytes. It is also used for the research of high blood pressure. For research use only.
- Orally active alpha-2-adrenoceptor agonist
- Exhibits antihypertensive activity
- Displays antiparasitic activity
- Interferes with ER stress-signalling
- Has protective effects in cardiac myocytes
- Used for research of high blood pressure
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Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.1% | 5 MG
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Betaxolol hydrochloride is a selective beta1 adrenergic receptor blocker, useful for research into hypertension and glaucoma. It acts as a cardioselective beta-adrenergic receptor blocking agent, potentially safer for patients with reactive airway disease due to reduced systemic beta 2- and beta 1-adrenergic receptor blockade compared to other agents. In vivo studies show it can attenuate anxiety-like behavior during early withdrawal from chronic cocaine administration in rats.
- Selective beta1 adrenergic receptor blocker
- Used for research of hypertension and glaucoma
- Cardioselective beta-adrenergic receptor blocking agent
- Attenuates anxiety-like behavior during cocaine withdrawal in rats
- Potentially safer for patients with reactive airway disease
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Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.1% | 10 MM * 1 ML
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Betaxolol hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. It is a cardioselective beta-adrenergic receptor blocking agent.
- Functions as a selective beta1 adrenergic receptor blocker
- Cardioselective beta-adrenergic receptor blocking agent
- Applicable for research in hypertension
- Applicable for research in glaucoma
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Medchemexpress LLC Terazosin hydrochloride | 63074-08-8 | 99.9% | 100 MG
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Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. It works by relaxing blood vessels and opening the bladder. It has potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment. This product is for research use only and not sold to patients.
- Competitive and orally active α1-adrenoceptor antagonist
- Relaxes blood vessels and opens the bladder
- Potential for benign prostatic hyperplasia (BPH) treatment
- Potential for high blood pressure treatment
- For research use only
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Medchemexpress LLC Dyclonine hydrochloride | 536-43-6 | 99.3% | 10 G
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Dyclonine hydrochloride is an orally effective ALDH covalent inhibitor that crosses the blood-brain barrier. It functions as a local anesthetic, capable of suppressing or relieving pain by blocking nerve impulse transmission. It also exhibits sensitizing activities for targeted cancer cells and possesses antibacterial and fungicidal properties, demonstrating significant activity against various bacteria and fungi.
- Orally effective ALDH covalent inhibitor
- Crosses the blood-brain barrier
- Functions as a local anesthetic
- Sensitizes cancer cells to cysteine and GSH deficiency
- Demonstrates bactericidal and fungicidal activity
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Medchemexpress LLC Lidocaine hydrochloride | 73-78-9 | 99.8% | 5 G
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Lidocaine hydrochloride (Lignocaine hydrochloride) is an amide derivative that inhibits sodium channels. It decreases the growth, migration, and invasion of gastric carcinoma cells by up-regulating miR-145 expression and inactivating the MEK/ERK and NF-κB signaling pathways. It is used to treat ventricular arrhythmia and is an effective tumor-inhibitor.
- Decreases cell proliferation
- Inhibits cell viability
- Increases the apoptotic cell rate
- Down-regulates Cyclin D1 and up-regulates p21 expression
- Causes completely reversible tail nerve block in rats
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Medchemexpress LLC Alfuzosin hydrochloride | 81403-68-1 | 99.7% | 5 MG
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Alfuzosin hydrochloride (SL 77499-10) is an orally active, selective, and competitive α1-adrenoceptor antagonist. It relaxes the muscles of the prostate and bladder neck, aiding in urination, and can be used in the study of benign prostatic hyperplasia (BPH).
- Orally active, selective, and competitive α1-adrenoceptor antagonist.
- Relaxes the muscles of the prostate and bladder neck, aiding in urination.
- Used in the study of benign prostatic hyperplasia (BPH).
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Medchemexpress LLC Moexipril hydrochloride | 82586-52-5 | 98.4% | 100 MG
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Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). It exhibits antihypertensive and neuroprotective effects. This compound is for research use only and not sold to patients.
- Inhibits angiotensin-converting enzyme (ACE)
- Exhibits antihypertensive and neuroprotective effects
- Significantly reduces the percentage of damaged neurons
- Attenuates Fe2+/3+-induced neurotoxicity
- Exhibits dose-dependent and antihypertensive effects in renal hypertensive rats, spontaneously hypertensive rats, and perinephritic hypertensive dogs
- Significantly reduces the infarct area on the mouse brain surface
- Significantly attenuates the cortical infarct volume in rats
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Medchemexpress LLC 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1) | 15622-65-8 | 99.8% | 1 ML
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Molindone hydrochloride is an orally active and brain-penetrant dopamine D2/D5 receptor antagonist. It exhibits antipsychotic and antidepressant-like activities, suppressing spontaneous locomotion and antagonizing apomorphine-induced emesis. It can be used for research related to neurological diseases.
- Orally active and brain-penetrant dopamine D2/D5 receptor antagonist.
- Shows antipsychotic and antidepressant-like activities.
- Suppresses spontaneous locomotion.
- Antagonizes apomorphine-induced emesis.
- Can be used for the research of neurological disease.
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Medchemexpress LLC Nebivolol hydrochloride | 152520-56-4 | 99.9% | 5 MG
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Nebivolol hydrochloride is an orally active beta receptor blocker with high beta(1)-receptor affinity. It possesses direct vasodilator properties and adrenergic blocking characteristics. It is used for the research of diseases such as hypertension, coronary artery disease, congestive heart failure, and ischemic heart disease.
- Improves endothelial dysfunction by stimulating endothelial nitric oxide synthase activity and through antioxidative properties.
- Inhibits human coronary artery smooth muscle cells and endothelial cells proliferation with IC50 values of ~6.0 μM after 1, 2, 4, 7, or 14 days of incubation (0.1 μM-10 μM).
- Induces a moderate rate of apoptosis in human coronary artery smooth muscle cells and endothelial cells after 24 hours of incubation (0.1 μM-10 μM).
- Increases NO formation and decreases endothelin-1 secretion in HaCEs (0.1, 1, 5, 10 μM, 4 days).
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